Cardiac Imaging Research
Multi-slice computed tomography (MSCT) has seen rapid advances in imaging technology that greatly facilitate accurate noninvasive coronary artery imaging. Research studies involving coronary computed tomography angiography (CCTA) are being conducted as investigator initiated single center trials as well as Beaumont managed state and national multi-center trials. These research studies focus on topics such as the safety and diagnostic efficacy of the procedure, cost effectiveness, radiation dose reduction techniques and appropriate use guidelines.
Key Research Areas
Current Cardiology CT/MRI research projects being conducted through the Beaumont Research Institute include:
- Radiation exposure continues to be one of the main concerns with a cardiac computed tomography (CT) scan. Blue Cross Blue Shield of Michigan (BCBSM) partnered with a consortium of practitioners across the state who contribute data to a registry. This registry, the Advanced Cardiac Imaging Consortium (ACIC), is designed to support the judicious use of the CCTA technology and monitor the safety and radiation dose of CT scans. The ACIC is funded by BCBSM and currently has 50 sites comprised of hospitals and imaging centers throughout the state. In the first 5 months of the registry, radiation exposure was reduced by 52% in patients undergoing CCTA at sites participating in the consortium. The Beaumont Research Coordinating Center serves as the contract research organization (CRO) for the project.
- A multi-center research trial was conducted by Beaumont which enrolled 750 patients at 16 sites across the country, to demonstrate the safety and diagnostic efficacy of the MSCT in low-risk chest pain patients presenting to Emergency Rooms. The study is closed to enrollment and is in the final stages of data analysis.
- Development of an umbrella study database for legacy CT research studies: Research Administration, the HIC, and Cardiology Research developed a study database to accommodate all of the data points from 7 legacy CT research studies. This project has over 4000 patient records entered into an electronic database and allows investigators to conduct a number of outcomes based projects by analyzing data from the large patient volume.
- A number of investigator-initiated studies are currently being conducted in the Cardiology Research Department involving coronary CT angiography. Projects include plaque imaging, different scan techniques such as triple rule out scans versus normal coronary CT scan, and the utility of CCTA in follow-up of graft patency in patients who have undergone coronary artery bypass graft surgery.
Numerous publications and presentations at national conferences have emerged from the cardiology CT research at Beaumont.
|Name||Research of Interest|
|Gilbert Raff, M.D.
Director of Cardiac CT/MRI, Director of Ministrelli Center for Advanced Cardiovascular Imaging
|Coronary CT Imaging|
|Kavitha Chinnaiyan, M.D.
Project Director, ACIC, Director, Advanced Imaging Education
|Women's Heart Disease, Coronary CT Imaging, Echocardiography, Cardiac MRI|
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